1 2 3 4 5 The response regulator SprE ( RssB ) modulates polyadenylation and mRNA stability in 6 Escherichia coli 7 8 Valerie
نویسندگان
چکیده
Department of Molecular Biology, Princeton University, Princeton, New Jersey 08544 10 Department of Genetics, University of Georgia, Athens, Georgia 30605 11 12 13 14 Running title: SprE modulates RNA polyadenylation 15 16 17 18 *Corresponding author. Mailing address: Department of Molecular Biology, Princeton 19 University, Princeton, NJ 08544. Phone: (609) 258-5899. Fax: (609) 258-2957. E-mail: 20 [email protected] 21 22 23 Copyright © 2009, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved. J. Bacteriol. doi:10.1128/JB.00870-09 JB Accepts, published online ahead of print on 18 September 2009
منابع مشابه
The response regulator SprE (RssB) modulates polyadenylation and mRNA stability in Escherichia coli.
In Escherichia coli, the adaptor protein SprE (RssB) controls the stability of the alternate sigma factor RpoS (sigma(38) and sigma(S)). When nutrients are abundant, SprE binds RpoS and delivers it to ClpXP for degradation, but when carbon sources are depleted, this process is inhibited. It also has been noted that overproduction of SprE is toxic. Here we show that null mutations in pcnB, encod...
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